Friedewald Equation:
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The Friedewald equation is a formula used to estimate LDL cholesterol (LDL-C) levels when direct measurement is not available. It calculates LDL-C using measurements of total cholesterol, HDL cholesterol, and triglycerides.
The calculator uses the Friedewald equation:
Where:
Explanation: The equation estimates LDL cholesterol by subtracting HDL cholesterol and one-fifth of triglycerides from total cholesterol.
Details: LDL cholesterol is often called "bad cholesterol" because high levels can lead to plaque buildup in arteries and increase risk of heart disease and stroke. Monitoring LDL levels is crucial for cardiovascular risk assessment.
Tips: Enter total cholesterol, HDL cholesterol, and triglycerides in mg/dL. All values must be valid (greater than 0). Note: This equation is not accurate when triglyceride levels exceed 400 mg/dL.
Q1: What is considered a low LDL level?
A: Generally, LDL levels below 100 mg/dL are considered optimal for heart health, though targets may vary based on individual risk factors.
Q2: When is the Friedewald equation not accurate?
A: The equation becomes less reliable when triglyceride levels exceed 400 mg/dL, in which case direct LDL measurement is recommended.
Q3: Why divide triglycerides by 5?
A: This factor represents the average cholesterol content in very-low-density lipoprotein (VLDL) particles, which carry most triglycerides in the blood.
Q4: How often should LDL be checked?
A: Adults should have their cholesterol checked every 4-6 years, or more frequently if they have risk factors for heart disease.
Q5: Can calculated LDL be negative?
A: Yes, in rare cases with very high triglyceride and low total cholesterol levels, the calculation may yield a negative result, indicating the equation's limitations.