Friedewald Equation:
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LDL (Low-Density Lipoprotein) cholesterol, often called "bad cholesterol," is calculated using the Friedewald equation from total cholesterol, HDL cholesterol, and triglyceride measurements. This provides an estimate of LDL levels without requiring direct measurement.
The calculator uses the Friedewald equation:
Where:
Explanation: The equation estimates LDL cholesterol by subtracting HDL cholesterol and one-fifth of triglycerides from total cholesterol.
Details: LDL cholesterol calculation is crucial for assessing cardiovascular risk, guiding lipid-lowering therapy, and monitoring treatment effectiveness in managing cholesterol levels.
Tips: Enter total cholesterol, HDL cholesterol, and triglycerides in mg/dL. All values must be valid (greater than 0). For accurate results, fasting blood samples are recommended.
Q1: Why calculate LDL instead of direct measurement?
A: Calculation is less expensive and widely available, though direct measurement may be needed in certain cases like very high triglycerides.
Q2: What are optimal LDL levels?
A: Optimal is generally <100 mg/dL, though targets vary based on individual cardiovascular risk factors.
Q3: When is the Friedewald equation not accurate?
A: When triglycerides are >400 mg/dL, in non-fasting samples, or with certain medical conditions affecting lipid metabolism.
Q4: How often should LDL be checked?
A: Generally every 4-6 years for adults, more frequently for those with elevated risk or on lipid-lowering therapy.
Q5: Can this calculation be used for children?
A: The equation is primarily validated for adults. Pediatric lipid assessment may require different approaches.