LDL-C Formula:
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The LDL Cholesterol formula calculates low-density lipoprotein cholesterol levels using total cholesterol, HDL cholesterol, and triglycerides measurements. This calculation provides an estimate of LDL-C levels without requiring direct measurement.
The calculator uses the LDL-C formula:
Where:
Explanation: This formula estimates LDL cholesterol by subtracting HDL cholesterol and a fraction of triglycerides from total cholesterol.
Details: LDL cholesterol is a major risk factor for cardiovascular disease. Accurate estimation helps in assessing cardiovascular risk and guiding treatment decisions for cholesterol management.
Tips: Enter total cholesterol, HDL cholesterol, and triglycerides in mmol/L. All values must be valid (greater than 0). For accurate results, use fasting lipid profile measurements.
Q1: Why use this formula instead of direct measurement?
A: This calculated method is more cost-effective and widely available than direct LDL measurement, though direct measurement may be more accurate in some cases.
Q2: What are optimal LDL-C levels?
A: Optimal LDL-C is generally below 2.6 mmol/L, though targets may vary based on individual cardiovascular risk factors.
Q3: When should this calculation be used?
A: This calculation is valid when triglycerides are below 4.5 mmol/L. For higher triglyceride levels, direct measurement is recommended.
Q4: Are there limitations to this formula?
A: The formula becomes less accurate with very high triglyceride levels (>4.5 mmol/L) and in certain metabolic conditions.
Q5: Should fasting samples be used?
A: Yes, for most accurate results, fasting samples (9-12 hours) are recommended as triglyceride levels can be affected by recent food intake.